Purine nucleotides
Apexbio Technology LLC 8-AZIDO-ATP 10UL 100 MM
8-Azido-ATP is a ribonucleoside triphosphate analog with an azido group substitution at the adenine C-8 position It acts primarily as an ATP mimic interacting with poly(A) polymerase (PAP) specifically illustrated using yeast poly(A) polymerase (yPAP) Incorporation of 8-azido-ATP into growing polyadenylation chains results in premature termination and moderately shorter poly(A) tails relative to natural ATP substrates Due to its chain-terminating capacity and altered substrate specificity 8-azido-ATP is applied in biochemical studies examining enzyme fidelity nucleotide selection mechanisms and RNA polymerase activity
Apexbio Technology LLC 2-O-METHYL-ATP 50UL 100 MM
2 -O-Methyl-ATP is a chemically modified derivative of ATP in which the hydroxyl group at the ribose 2 position is replaced with a methyl group This ribose modification confers resistance to nuclease-mediated degradation thereby increasing its biological stability The modified nucleotide is commonly employed in biomedical research to investigate RNA structure-function relationships and RNA modification pathways and to study interactions influencing RNA polymerase specificity and catalytic activity Additionally 2 -O-Methyl-ATP serves as a tool in probe design for RNA interference experiments and aids in elucidating intracellular metabolic pathways involving nucleotide analogs
Apexbio Technology LLC 2-AMINO-ATP 10UL 100 MM
2-Amino-ATP is a modified nucleotide structurally related to ATP (adenosine triphosphate) featuring an amino substitution at the adenine ring s 2-position It acts as an ATP analog capable of competitively binding at the active sites of ATP-dependent enzymes potentially modulating their enzymatic activity and influencing downstream signaling pathways In research settings 2-Amino-ATP serves as a molecular tool to examine substrate specificity mechanistic aspects of ATP-binding enzymes (e g kinases and ATPases) and nucleotide-dependent receptor interactions facilitating studies of nucleotide signaling and cellular metabolism
Sigma Aldrich Fine Chemicals Biosciences Adenosine 5-triphosphate disodium salt hydrate BioXtra, 99 (HPLC), from microbial, 34369-07-8, MFCD00150755
Adenosine 5-triphosphate disodium salt hydrate BioXtra, 99 (HPLC), from microbial
Sigma Aldrich Fine Chemicals Biosciences Adenosine 5-triphosphate disodium salt hydrate BioXtra, 99 (HPLC), from microbial, 34369-07-8, MFCD00150755
Adenosine 5-triphosphate disodium salt hydrate BioXtra, 99 (HPLC), from microbial
TARGETMOL CHEMICALS INC ADENOSINE AMINE CONGENER 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor. purity: 98%
TARGETMOL CHEMICALS INC GUANOSINE 5-DIPHOSPHATE 100MG
Also available in 5 mg 10 mg 25 mg 50 mg 200 mg 500 mg and bulk. Please contact Fisher for quotes. Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. purity: 98%
AdipoGen Guanosine 5-triphosphate Na
Chemical. CAS 36051-31-7. Formula C10H16N5O14P3 . xNa. Molecular Weight 523.18 free acid basis. Guanosine 5-triphosphate GTP trisodium salt activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. It also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA. GTP is involved in the initiation of peptide synthesis during the binding of formylmethionyl-tRNA F-met-tRNA to the ribosome. It is also involved in polypeptide chain elongation.
AdipoGen Guanosine 5-triphosphate Na
Chemical. CAS 36051-31-7. Formula C10H16N5O14P3 . xNa. Molecular Weight 523.18 free acid basis. Guanosine 5-triphosphate GTP trisodium salt activates the signal transducing G proteins which are involved in various cellular processes including proliferation, differentiation and activation of several intracellular kinase cascades. Proliferation and apoptosis are regulated in part by the hydrolysis of GTP by small GTPases Ras and Rho. Another type of small GTPase, Rab, plays a role in the docking and fusion of vesicles and may also be involved in vesicle GTP functions as a carrier of phosphates and pyrophosphates involved in channeling chemical energy into specific biosynthetic pathways. It also serves as an energy-rich precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA. GTP is involved in the initiation of peptide synthesis during the binding of formylmethionyl-tRNA F-met-tRNA to the ribosome. It is also involved in polypeptide chain elongation.
Selleck Chemical LLC Adenosine S1647-10mM/1mL
Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a -N9-glycosidic bond
TARGETMOL CHEMICALS INC Guanosine 5-diphosphate disodi
Also available in 5 mg, 10 mg, 25 mg, 50 mg, 200 mg, 500 mg and bulk. Please contact Fisher for quotes. Guanosine 5'-diphosphate disodium salt (5'-GDP-Na2) is a nucleoside diphosphate, is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway. Purity 98%